Reagents & Accessories
Biological Sample Management
IntegenX offers innovative and robust solutions for standardized, ambient temperature transport and preservation of biological samples, from collection to storage to downstream application. Complementing our instrument product lines, our reagents and accessories facilitate advances in medicine and healthcare by enabling our customers to fully capture biological sample value.
GenTegra – A Dry State Ambient Temperature Environment for Storing DNA and RNA
Our reagent lines shift the paradigm for biosample management from wet, refrigerated sample storage to dry state ambient temperature storage of purified DNA and RNA. Nucleic acid integrity is no longer a concern with long term storage at room temperature. GenTegra™ DNA, for purified nucleic acid storage in a water-soluble inert mineral matrix, ensures sample stability and is compatible with the most demanding molecular assays. GenTegra™ RNA is an inert chemical matrix that inactivates trace RNase in the liquid phase, providing an added level of RNA stability during sample handling. GenTegra DNA and GenTegra RNA products provide smart, environmentally and financially sustainable solutions which you can apply and integrate into your existing cryostorage system. The value of genomic samples is priceless and researchers now have an alternative for managing their DNA and RNA samples that gives them peace of mind.
GenTegra DNA and GenTegra RNA products provide smart, environmentally and financially sustainable solutions which you can apply and integrate into your existing cryostorage system. The value of genomic samples is priceless and researchers now have an alternative for managing their DNA and RNA samples that gives them peace of mind.
GenSolve – A Proprietary Chemistry for Recovering Samples Stored on Paper
GenSolve is a robust chemistry enables efficient recovery of high quality DNA from biosamples such as blood, buffy coat and plasmid DNA that have been dried on paper and banked at ambient temperature.
Ambient Temperature Biosample Storage: Historical, Current and Future Applications
The idea of biosample storage at ambient temperature has an interesting history that spans at least 55 years back to 1962 when Dr. Guthrie invented the Guthrie card, a paper based matrix for newborn screening. Since then, applications for samples stored at ambient temperature in the dry state have expanded substantially. Blood storage on various forms of paper are commonly used in public health screening, agriculture, and forensics. These markets routinely analyze DNA, serology, and small molecules, with acceptance growing widely over the past 20 years. In fact, in the US every one of the more than 4 million babies born every year have blood samples collected on Guthrie cards for the screening of genetic diseases.
Markets that currently utilize ambient temperature biosample storage platforms need to:
• Analyze thousands to millions of samples in parallel.
• Maintain a high-quality of sample during transport.
• Achieve operational simplicity while reducing costs.
All of these needs can only be addressed by employing some form of ambient temperature storage.
Life scientists typically work with a fewer number samples and do not express the same level of need regarding efficiencies of scale. Recent advances in massively parallel and high-throughput genetic analysis have opened the window for personalized genomics and population studies that utilize thousands to millions of biosamples. As a result, sample processing has become the bottleneck in conducting research. In response to this need, our reagent products are built upon decades of previous work in ambient temperature storage and provide solutions for long-term stability and novel technologies for nucleic acid storage and biomarker storage.
As more and more genetic discoveries are transformed into functional clinical tests and therapies, it is reasonable to expect that the needs outlined above will expand to clinical markets as well. Furthermore, spiraling healthcare costs will force the development of more efficient sample handling. These areas will most certainly be the focus of future development in ambient temperature biosample storage.